8:00 am Coffee & Networking
8:45 am Chair’s Opening Remarks
Contrasting Application of Batch vs Flow to Make the Right Decision for Your Process and Shorten Development Times
9:00 am Handling Multi-Step Reactions Using Flow and Batch Processes to Optimize Your Process Development and Manufacturing
Synopsis
- Planning your process development strategy to accommodate both flow and batch processes
- Harmonizing the switch between batch and flow throughout your process
- Benefit of using multi-step reactions for your process
9:30 am Session Reserved for Continuus
10:00 am Understanding Key Drivers in Choosing Flow Processes to Streamline Your Process Development
Synopsis
- Case study: When the chemistry fits better with flow
- Cost benefits of using flow over batch processes
- Overall economic benefits of using flow chemistry
10:30 am Morning Refreshments & Networking
Automation and Self-Optimization of Flow Technology to Reduce Overall Turnaround Time
11:30 am Case Study: Pairing Flow Chemistry with Harmonious Emerging Technologies to Reduce Turnaround Time
Synopsis
- Latest technologies applicable to flow processes
- Where new technologies will fit into your flow process
- Is end-to-end automation a possibility?
12:00 pm Session Reserved for Axplora
12:10 pm A Journey Towards Developing an Automated Continuous Flow Platform for the Preparation of Active Pharmaceutical Ingredient Intermediates
Synopsis
- Integrating the right unit ops for your process and chemistry
- What is required to achieve automation?
- Selecting an automation strategy that is fit for purpose
Optimization of Reactions & Workups to Accelerate Speed to Market
12:40 pm CMAC Data Lab: Cyberphysical Systems and Digital Transformation of CMC
Synopsis
Key topics that will be addressed from CMAC’s research programme:
- Overview of predictive toolbox development for crystallisation (CCS) and drug product (MCS+)
- Building the data fabric to support product and process development
- Datafactories and automated workflows to accelerate development
- Challenges & opportunities for industrial digital technologies in CMC
1:10 pm Lunch & Networking
Automation and Self-Optimization of Flow Technology to Reduce Overall Turnaround Time
2:10 pm Case Study: Upstream Automation for Reaction Optimization
Synopsis
- Technologies applicable to the process development and their benefits
- Appropriate equipment and materials to use
- Overall strategy to execute an automated development
2:40 pm Applying Automation in Flow Chemistry to Improve Overall Efficiency of Your Process
Synopsis
- Key drivers in introducing automation into flow processes
- How automation improves capabilities for scale up
- Why automation of your process improves economies of scale
3:10 pm Round table discussion: Automating the Manufacturing Process for Reaction Optimization
Synopsis
In a round table discussion, the participants discuss the specified topic assigned to
that table
- Technologies applicable to the manufacturing process and their benefits
- Reducing turnaround time, labour costs and material waste
- Integrating automated feedback control systems
3:45 pm Afternoon Refreshments & Networking
Building Relations in Flow Processes: Chemists & Engineers
4:30 pm Building a Flow Process Dream Team: Principles and Practices
Synopsis
- Distill the principles and practices for building effective teams for flow chemistry process development and manufacturing
- From the bench to the production suite, flow chemistry presents unique challenges. Equipping teams with the right support and expertise can help to minimize frustration and unlock innovation
5:00 pm Panel Discussion: Coming Together as Chemists and Engineers for Flow
Synopsis
- What are the most important challenges you face and how do you approach this challenge (question for both chemist and engineer)
- Discussing different perspectives for common challenges
- How to structure agreements to set up appropriate incentives for process developers and manufacturers