Development of a Continuous Photochemical Bromination/Alkylation Sequence En Route to AMG 423

Time: 11:30 am
day: Day One


  • Discussion of batch process – Detailed discussion of the batch process and problems encountered
    that could be addressed using flow chemistry to improve robustness and minimize waste output
  • Development of a flow process – An overview of the development of the flow process including
    reaction screening, optimization, and lab scale demonstration will be presented
  • Kinetic and mechanistic aspects – Kinetic and mechanistic aspects of the flow process will be